Alzheimer's research and help, in plain English.
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Latest news
Approvals, trial results and policy changes, from established outlets.
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Cholesterol transport protein emerges as possible target for Parkinson's treatment
Parkinson's disease (PD) is a neurodegenerative condition that causes the progressive loss of dopamine-producing neurons in a brain region called the substantia nigra.
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Extra weight may be aging your brain faster than you think
A major 24-year study involving more than 8,200 adults suggests that excess body weight may accelerate brain aging, leading to faster declines in memory, concentration, and decision-making skills. …
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Landmarks worldwide to light up teal today for Alzheimer’s awareness
Today, landmarks around the world will be lit up teal as advocates globally work to raise awareness — throughout this entire month — about Alzheimer’s disease. …
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Enhancing the cell's natural recycling center improves Alzheimer's features in animal models
A defining feature of Alzheimer's disease is the abnormal, sustained accumulation of protein aggregates such as tau inside brain cells, which disrupts the cells' normal functions. …
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Medicare spending rises after private equity buys hospices
A study of for-profit hospices acquired by private equity firms found that Medicare spending rose by 5.9% per hospice stay after acquisition, compared with similar for-profit hospices that weren't acquired. …
Latest research
The newest studies in the library that score 67 or more out of 100 (2,314 of the 27,380 do), with their peer-review status.
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Evaluating a primary care pharmacist-led intervention to reduce opioid use for persistent non-cancer pain: the PROMPPT cluster randomised controlled trial protocol
The PROMPPT trial will assess whether review by trained clinical pharmacists working in general practices can support safe opioid reduction without compromising pain management and quality of life. (+1 more on the study page)
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Midlife and Late-Life Alzheimer Disease Blood Biomarkers and 11-Year Cognitive Decline
Midlife p-tau181 was associated with faster 11-year memory decline beginning 20 years later in the ARIC cohort, which underscores a potentially long prodromal phase of cognitive decline that could precede dementia onset. (+4 more on the study page)
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Presymptomatic plasma biomarkers in autosomal dominant Alzheimer's disease: sequence and timing
Nine proteins (amyloid-beta 42 (Aβ42), beta-secretase 1 (BACE1), glial fibrillary acidic protein (GFAP), pTau181, pTau231, pTau217, t0tal tau (MAPT), neurofilament light (NfL) and acetylcholinesterase (AChE)) robustly differed between carriers and non-carriers cross-sectionally. (+4 more on the study page)
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Longitudinal Multimodal Retinal Imaging in Cognitively Normal Apolipoprotein E4 Carriers and Noncarriers
This study analyzed 871 eyes from 439 participants (230 APOE ε4 noncarriers and 209 carriers). (+4 more on the study page)
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Sex-specific brain reserve and progression from mild cognitive impairment to Alzheimer's disease dementia
Females with MCI exhibited greater baseline GMV than males primarily in the thalamus, caudate, cerebellum, postcentral gyrus, and middle cingulate gyrus, with no differences at the AD stage. (+2 more on the study page)
The research library
27,380 studies in plain English across 32 subjects. Each is scored and links to the original paper.
Search and filter the research →
Browse by subject · Links the news suggests that nobody has tested
A few key figures
Americans age 65+ living with Alzheimer's dementia
Alzheimer's Association, 2025 Alzheimer's Disease Facts and Figures (Alzheimer's & Dementia)Alzheimer's prevalence by age: 85+
Alzheimer's Association, 2025 Facts and FiguresIncrease in U.S. Alzheimer's deaths, 2000-2022
Alzheimer's Association, 2025 Facts and FiguresFamily/unpaid dementia caregivers in the U.S.
Alzheimer's Association, 2026 Alzheimer's Disease Facts and FiguresDementia caregivers who rated emotional stress of caregiving as high or very high
Alzheimer's Association, 2025 Facts and FiguresLifetime cost of care per person with dementia
Alzheimer's Association, 2025 Facts and FiguresPeople living with dementia worldwide
WHO, Dementia Fact SheetShare of dementia cases potentially preventable/delayable via modifiable risk factors
Lancet Commission on dementia prevention, intervention, and care, 2024 report (summarized by Alzheimer's Disease International)FDA-cleared Lumipulse blood test accuracy for detecting amyloid pathology
FDA press announcement, Lumipulse G pTau217/Beta-Amyloid 1-42 Plasma Ratio clearance